circRNA basic information
circBase ID: -
Name: hsa_circ_SFMBT2
Synonym: circ-SFMBT2
Host Gene: SFMBT2
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0005233
MONDO name: non-small cell lung carcinoma
Disease details: non-small cell lung cancer / NSCLC
Disease DO ID:
 3908
Disease MeSH ID:
 D002289
Disease NCIt ID:
 C2926
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

-
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UN
Associated gene: ADAM10
Associated microRNA: miR-7-5p
Biological function: Regulates the biological behavior of non-small cell lung cancer cells.
Molecular mechanism: circ-SFMBT2 acts through the miR-7-5p/ADAM10 axis.
Biological pathway or process:

ceRNA regulation (other); other pathway/process (other)
Detected method:
Q
Validation methods:

RT-qPCR; Luciferase Reporter Assay; Transfection; CCK8; Transwell Assay; Western Blot
Clinical significance:

-
Description:

This study investigated circ-SFMBT2 in non-small cell lung cancer cells. The available title indicates that circ-SFMBT2 affects NSCLC cell biological behavior by targeting the miR-7-5p/ADAM10 axis.
Confidence score:

0.5223
Other information
Title:

[Effect of circ-SFMBT2 on the biological behavior of non-small cell lung cancer cells by targeting the miR-7-5p/ADAM10 axis].

Journal: Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics
Published: 2022
PubMed ID: 35076912
Study type:

biological research
Data availability: -
Code availability: -