circRNA basic information
circBase ID: hsa_circ_0101692
Name: hsa_circ_EGLN3
Synonym: circ_0101692
Host Gene: hsa-miR-384
 
 
 
Disease basic information
DO ID:
 4467
DO name: clear cell renal cell carcinoma
Disease details: clear cell renal cell carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human embryonic kidney cells (HEK293), ccRCC cell lines (786-O, 769-P)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: FN1
Associated microRNA: hsa-miR-384
Biological function: Cell growth, migration and viability were decreased whereas cell apoptosis was stimulated when circ_0101692 was knockdown.
Molecular mechanism: circ_0101692/hsa-miR-384/FN1 axis, miRNA sponge
Survival: -
Supported No.:
 2
Description:

This points out that circ_0101692/miR-384/FN1 axis might be a prospective target implemented for the future treatment of ccRCC.
Other information
Title:

Circ_0101692 knockdown retards the development of clear cell renal cell carcinoma through miR-384/FN1 pathway.

Journal: Transl Oncol
Published: 2023/1/7
PubMed ID: 36608542