circRNA basic information
circBase ID: hsa_circ_0083964
Name: hsa_circ_ASH2L
Synonym: Circ_0083964
Host Gene: hsa-miR-204-5p
 
 
 
Disease basic information
DO ID:
 7148
DO name: rheumatoid arthritis
Disease details: rheumatoid arthritis
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: FLSs, RA-FLSs
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: YY1
Associated microRNA: hsa-miR-204-5p
Biological function: Circ_0083964 downregulation constrained proliferation, metastasis and inflammation and facilitated apoptosis in RA-FLSs.
Molecular mechanism: circ_0083964/hsa-miR-204-5p/YY1 axis, miRNA sponge
Survival: -
Supported No.:
 3
Description:

Circ_0083964 inhibition confined RA development by sponging miR-204-5p to hamper the YY1 level, which will provide a theoretical basis for the treatment of RA.
Other information
Title:

Circ_0083964 knockdown impedes rheumatoid arthritis progression via the miR-204-5p-dependent regulation of YY1.

Journal: J Orthop Surg Res
Published: 2022/12/23
PubMed ID: 36550514