circRNA basic information
circBase ID: -
Name: hsa_circ_ACVR2A
Synonym: circACVR2A
Host Gene: ACVR2A
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: extracellular vesicle
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0008315
MONDO name: prostate cancer
Disease details: prostate cancer / PCa
Disease DO ID:
 10283
Disease MeSH ID:
 D011471
Disease NCIt ID:
 C7378
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

EV-enriched plasma
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: not specified
Molecular mechanism: not specified
Biological pathway or process:

not specified
Detected method:
M
Validation methods:

Microarray; Clinical Sample Validation
Clinical significance:

elevated in EV-enriched plasma from MPC patients relative to controls
Description:

circACVR2A is detectable in EV-enriched plasma and is elevated in patients with metastatic prostate cancer compared with cancer-free controls, supporting potential as a minimally invasive biomarker. No mechanism is studied.
Confidence score:

0.2995
Other information
Title:

The transcriptional landscape and biomarker potential of circular RNAs in prostate cancer.

Journal: Genome medicine
Published: 2022
PubMed ID: 35078526
Study type:

combined biological and clinical study
Data availability: Additional files 10-13, Tables S8-11
Code availability: -