circRNA basic information
circBase ID: hsa_circ_0079891
Name: -
Synonym: circ_0079891
Host Gene: -
Genomic location(hg19): chr7:37250990-37382367:-
Genomic location(hg38): chr7:37211385-37342763:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0005075
MONDO name: thyroid gland papillary carcinoma
Disease details: papillary thyroid cancer
Disease DO ID:
 3969
Disease MeSH ID:
 -
Disease NCIt ID:
 C4035
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

PTC tissues; paired normal tissues
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DN
Associated gene: -
Associated microRNA: hsa-miR-361-3p, hsa-miR-1272, hsa-miR-182-5p, hsa-miR-384, hsa-miR-512-5p, hsa-miR-515-5p, hsa-miR-558, hsa-miR-576-3p, hsa-miR-647, hsa-miR-665, hsa-miR-1206, hsa-miR-1243, hsa-miR-1256, hsa-miR-1270
Biological function: Differentially expressed circRNA potentially involved in PTC progression via predicted circRNA-miRNA-mRNA interactions.
Molecular mechanism: Predicted miRNA sponge/ceRNA mechanism.
Biological pathway or process:

ceRNA regulation (other)
Detected method:
Q
M
Validation methods:

Microarray; RT-qPCR; RNase R Treatment; Clinical Sample Validation; Bioinformatics Analysis
Clinical significance:

Potential PTC biomarker candidate.
Description:

hsa_circ_0079891 is down-regulated in PTC tissues and was validated by qRT-PCR. It is predicted to interact with multiple miRNAs, including hsa-miR-361-3p and hsa-miR-182-5p, suggesting involvement in PTC-related ceRNA regulation.
Confidence score:

0.5135
Other information
Title:

Integrative analysis of circular RNA regulatory network in papillary thyroid carcinoma.

Journal: American journal of cancer research
Published: 2023
PubMed ID: 37818060
Study type:

combined bioinformatics and clinical study
Data availability: GSE93522; GSE173299; TCGA-THCA; CircInteractome; CircBank; TargetScan; CSCD
Code availability: -