circRNA basic information
circBase ID: hsa_circ_0092278
Name: -
Synonym: -
Host Gene: -
Genomic location(hg19): chr17:4797948-4798348:+
Genomic location(hg38): chr17:4894653-4895053:+
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0005075
MONDO name: thyroid gland papillary carcinoma
Disease details: papillary thyroid cancer
Disease DO ID:
 3969
Disease MeSH ID:
 -
Disease NCIt ID:
 C4035
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

PTC tissues; paired normal tissues
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-1236-3p, hsa-miR-149-5p, hsa-miR-331-3p, hsa-miR-432-5p, hsa-miR-502-5p
Biological function: Newly discovered overlapping circRNA potentially involved in PTC-related circRNA-miRNA-mRNA regulation.
Molecular mechanism: Predicted miRNA sponge/ceRNA mechanism.
Biological pathway or process:

ceRNA regulation (other)
Detected method:
Q
M
Validation methods:

Microarray; RT-qPCR; RNase R Treatment; Clinical Sample Validation; Bioinformatics Analysis
Clinical significance:

Potential PTC biomarker candidate.
Description:

hsa_circ_0092278 was newly identified and validated as an up-regulated circRNA in PTC. It is predicted to interact with five miRNAs, including hsa-miR-502-5p, within a potential ceRNA network.
Confidence score:

0.5135
Other information
Title:

Integrative analysis of circular RNA regulatory network in papillary thyroid carcinoma.

Journal: American journal of cancer research
Published: 2023
PubMed ID: 37818060
Study type:

combined bioinformatics and clinical study
Data availability: GSE93522; GSE173299; TCGA-THCA; CircInteractome; CircBank; TargetScan; CSCD
Code availability: -