circRNA basic information
circBase ID: hsa_circ_0061259
Name: hsa_circ_BAGE2
Synonym: CircBAGE2
Host Gene: BAGE2
Genomic location(hg19): chr21:11038727-11058323:-
Genomic location(hg38): chr21:10454134-10473728:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0008315
MONDO name: prostate cancer
Disease details: prostate cancer
Disease DO ID:
 10283
Disease MeSH ID:
 D011471
Disease NCIt ID:
 C7378
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

-
Cell lines:

RWPE-1; 22RV1
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: PDCD10
Associated microRNA: miR-103a
Biological function: may be relevant to the progression of PCa
Molecular mechanism: predicted circBAGE2-miR-103a interaction; potential effect on PDCD10 via miR-103a
Biological pathway or process:

proliferation (other); ceRNA regulation (other)
Detected method:
Q
S
Validation methods:

circRNA-seq; RNase R Treatment; RT-qPCR; Bioinformatics Analysis
Clinical significance:

-
Description:

CircBAGE2 (hsa_circ_0061259) is up-regulated in 22RV1 vs RWPE-1 and is suggested to be relevant to PCa progression, potentially via interaction with miR-103a and downstream PDCD10.
Confidence score:

0.4276
Other information
Title:

Profiling and bioinformatics analyses of differential circular RNA expression in prostate cancer cells.

Journal: Future science OA
Published: 2018
PubMed ID: 30416748
Study type:

biological research
Data availability: -
Code availability: -