| Expression pattern: |
UP |
| Associated gene: |
- |
| Associated microRNA: |
- |
| Biological function: |
cSMARCA5 is associated with poor 3-year overall survival and promotes radiotherapy resistance in patients with HCC. |
| Molecular mechanism: |
The study did not experimentally define a molecular mechanism; it reported clinical associations between high cSMARCA5 expression, poor prognosis, and radiotherapy resistance. |
| Biological pathway or process: |
radioresistance (promotes) |
| Detected method: |
Q
|
| Validation methods: |
RT-qPCR; Clinical Sample Validation; Cohort Study; Survival Analysis |
| Clinical significance: |
Higher cSMARCA5 expression is related to poorer 3-year overall survival and radiotherapy resistance in HCC patients. |
| Description: |
This clinical case-control study found that cSMARCA5 is up-regulated in HCC tumor tissues compared with paracancerous tissues. High cSMARCA5 expression is associated with poorer 3-year overall survival and radiotherapy resistance, suggesting potential prognostic and treatment-response value in HCC. |
| Confidence score: |
0.4758 |