circRNA basic information
circBase ID: hsa_circ_0026527
Name: hsa_circ_EIF4B
Synonym: -
Host Gene: EIF4B
Genomic location(hg19): chr12:53421565-53433486:+
Genomic location(hg38): chr12:53027781-53039702:+
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0002974
MONDO name: cervical cancer
Disease details: cervical cancer
Disease DO ID:
 4362
Disease MeSH ID:
 -
Disease NCIt ID:
 C9311
Disease ICD11 ID:
 1256072522
Disease OMIM ID:
 603956
Species: Human
Species details: Homo sapiens
Tissue specimen:

-
Cell lines:

Caski; SiHa; C33A
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-15b-3p
Biological function: -
Molecular mechanism: Potential miRNA sponge (predicted)
Biological pathway or process:

ceRNA regulation (other)
Detected method:
Q
M
Validation methods:

Microarray; RT-qPCR; Bioinformatics Analysis; Transfection
Clinical significance:

-
Description:

hsa_circ_0026527 (EIF4B-derived) is up-regulated upon HPV16 E7 knockdown in HPV16-positive cervical cancer cell lines and is predicted to interact with hsa-miR-15b-3p, indicating a potential E7-linked circRNA-miRNA regulatory relationship.
Confidence score:

0.3684
Other information
Title:

Human papillomavirus 16 E7 oncoprotein alters the expression profiles of circular RNAs in Caski cells.

Journal: Journal of Cancer
Published: 2018
PubMed ID: 30405847
Study type:

biological research
Data availability: -
Code availability: -