circRNA basic information
circBase ID: -
Name: hsa_circ_PRKCH
Synonym: CircPRKCH
Host Gene: hsa-miR-145
 
 
 
Disease basic information
DO ID:
 8398
DO name: osteoarthritis
Disease details: osteoarthritis
Species: human
Species details: human
Sample type: cell line, PDX
Sample type details: 293T
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: HGF
Associated microRNA: hsa-miR-145
Biological function: chondrocyte apoptosis and ECM degradation
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 3
Description:

circPRKCH promoted chondrocyte apoptosis and ECM degradation via the miR-145/HGF axis in OA.
Other information
Title:

CircPRKCH modulates extracellular matrix formation and metabolism by regulating the miR-145/HGF axis in osteoarthritis.

Journal: Arthritis Res Ther
Published: 2022/9/7
PubMed ID: 36068644