circRNA basic information
circBase ID: hsa_circ_0000069
Name: hsa_circ_STIL
Synonym: circSTIL_025
Host Gene: STIL
Genomic location(hg19): chr1:47745912-47748131:-
Genomic location(hg38): chr1:47280240-47282459:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0005380
MONDO name: osteonecrosis
Disease details: steroid-induced osteonecrosis of the femoral head
Disease DO ID:
 0080008, 10159
Disease MeSH ID:
 D010020
Disease NCIt ID:
 C34880; C35476
Disease ICD11 ID:
 536467755
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

peripheral blood
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: miR-345-5p
Biological function: -
Molecular mechanism: circRNA-miRNA-mRNA interaction network prediction
Biological pathway or process:

ceRNA regulation (other)
Detected method:
Q
S
Validation methods:

circRNA-seq; RT-qPCR; Clinical Sample Validation; Bioinformatics Analysis
Clinical significance:

-
Description:

circ_0000069 (circSTIL_025) is up-regulated in peripheral blood of SONFH patients and was validated by qRT-PCR; it was also part of the study’s predicted circRNA-miRNA-mRNA network (miR-345-5p as a putative interacting miRNA).
Confidence score:

0.4685
Other information
Title:

Expression Profile Analysis of Differentially Expressed Circular RNAs in Steroid-Induced Osteonecrosis of the Femoral Head.

Journal: Disease markers
Published: 2019
PubMed ID: 31827647
Study type:

combined biological and clinical study
Data availability: PRJNA522627
Code availability: -