circRNA basic information
circBase ID: hsa_circ_0006856
Name: hsa_circ_MAP3K5
Synonym: circ‐MAP3K5
Host Gene: MAP3K5
Genomic location(hg19): chr6:137015277-137019820:-
Genomic location(hg38): chr6:136694139-136698682:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0007959
MONDO name: medulloblastoma
Disease details: medulloblastoma
Disease DO ID:
 0050902, 0060104
Disease MeSH ID:
 D008527
Disease NCIt ID:
 C3222
Disease ICD11 ID:
 290815825
Disease OMIM ID:
 155255
Species: Human
Species details: Homo sapiens
Tissue specimen:

medulloblastoma tissues; normal cerebellum tissues
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DN
Associated gene: -
Associated microRNA: -
Biological function: -
Molecular mechanism: -
Biological pathway or process:

not specified
Detected method:
Q
S
Validation methods:

RNA-seq; RT-qPCR; Clinical Sample Validation
Clinical significance:

-
Description:

circ‐MAP3K5 is significantly downregulated in medulloblastoma tissues compared with normal cerebellum and was confirmed by RT-qPCR, but the paper does not report downstream functional assays or mechanisms for this circRNA.
Confidence score:

0.3588
Other information
Title:

Dysregulated circular RNAs in medulloblastoma regulate proliferation and growth of tumor cells via host genes.

Journal: Cancer medicine
Published: 2018
PubMed ID: 30402980
Study type:

combined biological and clinical study
Data availability: -
Code availability: -