circRNA basic information
circBase ID: hsa_circ_0078768
Name: hsa_circ_FAM120B
Synonym: circFAM120B
Host Gene: FAM120B
Genomic location(hg19): chr6:170626457-170632347:+
Genomic location(hg38): chr6:170317369-170323259:+
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0005115
MONDO name: temporal lobe epilepsy
Disease details: temporal lobe epilepsy
Disease DO ID:
 3328
Disease MeSH ID:
 D004833
Disease NCIt ID:
 C177244
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

human epileptic and control tissues
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: Expression was significantly elevated in epileptic tissues; no functional role was experimentally characterized.
Molecular mechanism: -
Biological pathway or process:

not specified
Detected method:
Q
S
Validation methods:

RT-qPCR; RNA-seq; Clinical Sample Validation
Clinical significance:

-
Description:

circFAM120B was selected from RNA-Seq data as an up-regulated candidate circRNA in TLE and was confirmed by RT-qPCR to be significantly elevated in epileptic tissues. No mechanistic or functional experiments were reported for this circRNA.
Confidence score:

0.3588
Other information
Title:

CircRNA SRRM4 affects glucose metabolism by regulating PKM alternative splicing via SRSF3 deubiquitination in epilepsy.

Journal: Neuropathology and applied neurobiology
Published: 2023
PubMed ID: 36168302
Study type:

clinical study
Data availability: The data that support the findings of this study are available from the corresponding author upon reasonable request.
Code availability: -