circRNA basic information
circBase ID: -
Name: hsa_circ_EPHA3
Synonym: cEPHA3
Host Gene: EPHA3
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0004985
MONDO name: bipolar disorder
Disease details: bipolar disorder
Disease DO ID:
 3312
Disease MeSH ID:
 D001714
Disease NCIt ID:
 C34423
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

postmortem human medial frontal gyrus tissue
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: EPHA3
Associated microRNA: -
Biological function: implicated in developmental processes in the central nervous system
Molecular mechanism: -
Biological pathway or process:

other pathway/process (other)
Detected method:
S
Validation methods:

RNA-seq; Bioinformatics Analysis
Clinical significance:

-
Description:

cEPHA3 is reported as up-regulated in postmortem medial frontal gyrus tissue from bipolar disorder patients versus controls based on circRNA differential expression from non-polyadenylated RNA-seq. The authors note potential relevance of EPHA3-related developmental processes in the central nervous system.
Confidence score:

0.1768
Other information
Title:

Coding and Non-Coding RNA Abnormalities in Bipolar Disorder.

Journal: Genes
Published: 2019
PubMed ID: 31752442
Study type:

combined biological and clinical study
Data availability: -
Code availability: -