circRNA basic information
circBase ID: hsa_circ_0004365
Name: hsa_circ_SEMA3C
Synonym: circ_0004365
Host Gene: SEMA3C
Genomic location(hg19): chr7:80418621-80440017:-
Genomic location(hg38): chr7:80789305-80810701:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0005494
MONDO name: triple-negative breast carcinoma
Disease details: triple-negative breast cancer / TNBC
Disease DO ID:
 0060081
Disease MeSH ID:
 D064726
Disease NCIt ID:
 C71732
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

adjacent frozen tissues
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DN
Associated gene: AGO2, EIF4A3, ELAVL1 (HuR), IGF2BP1, IGF2BP2, IGF2BP3, PTBP1
Associated microRNA: -
Biological function: Putatively participates in TNBC-related gene regulation via predicted RBP binding (in silico).
Molecular mechanism: Predicted circRNA-RBP interaction (CircInteractome/CLIP-seq-based).
Biological pathway or process:

not specified
Detected method:
S
Validation methods:

RNA-seq; Bioinformatics Analysis
Clinical significance:

-
Description:

hsa_circ_0004365 is down-regulated in TNBC in RNA-seq and was included in circRNA-RBP interaction prediction analyses, suggesting a potential role in gene regulation via RBPs.
Confidence score:

0.1768
Other information
Title:

Triple-Negative Breast Cancer circRNAome Reveals Hsa_circ_0072309 as a Potential Risk Biomarker.

Journal: Cancers
Published: 2022
PubMed ID: 35805051
Study type:

bioinformatics study
Data availability: PRJNA808398
Code availability: -