circRNA basic information
circBase ID: hsa_circ_0000375
Name: -
Synonym: -
Host Gene: -
Genomic location(hg19): chr12:6657590-6657991:-
Genomic location(hg38): chr12:6548424-6548825:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0005575
MONDO name: colorectal cancer
Disease details: colorectal cancer
Disease DO ID:
 5672, 9256
Disease MeSH ID:
 -
Disease NCIt ID:
 C4978
Disease ICD11 ID:
 -
Disease OMIM ID:
 114500
Species: Human
Species details: Homo sapiens
Tissue specimen:

CRC tissues; normal colorectal tissues
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UN
Associated gene: P2RY12, SSTR2, CASR, NPY2R, GNG7, AGT, PTGDR2
Associated microRNA: hsa-miR-215-3p, hsa-miR-185-5p, hsa-miR-3194-5p, hsa-miR-671-5p, hsa-miR-486-3p, hsa-miR-3652, hsa-miR-605-5p
Biological function: unknown
Molecular mechanism: ceRNA network (circRNA-miRNA-mRNA) proposed by bioinformatics prediction
Biological pathway or process:

ceRNA regulation (other)
Detected method:
M
Validation methods:

Microarray; Bioinformatics Analysis
Clinical significance:

-
Description:

hsa_circ_0000375 was selected as one of five crucial circRNAs in a CRC-related ceRNA hub subnetwork built from GEO/TCGA-derived differential expression and interaction predictions. No experimental functional validation in CRC was provided.
Confidence score:

0.1768
Other information
Title:

Analysis of Circular RNA-Related Competing Endogenous RNA Identifies the Immune-Related Risk Signature for Colorectal Cancer.

Journal: Frontiers in genetics
Published: 2020
PubMed ID: 32582276
Study type:

bioinformatics study
Data availability: GSE126095; TCGA
Code availability: -