circRNA basic information
circBase ID: -
Name: hsa_circ_DNAH14
Synonym: chr1_224952669_224974153_+
Host Gene: DNAH14
Genomic location(hg19): chr1:225140371-225161855:+
Genomic location(hg38): chr1:224952669-224974153:+
Subcellular localization: exosome
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0004992
MONDO name: cancer
Disease details: cancer
Disease DO ID:
 0050686, 0050687, 162
Disease MeSH ID:
 -
Disease NCIt ID:
 C9305
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

plasma exosomes
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UN
Associated gene: DNAH14, chr1:224952669:G>A
Associated microRNA: -
Biological function: -
Molecular mechanism: related to a splice acceptor variant of DNAH14 (chr1:224952669:G>A)
Biological pathway or process:

not specified
Detected method:
S
Validation methods:

RNA-seq; Bioinformatics Analysis
Clinical significance:

-
Description:

chr1_224952669_224974153_+ is a DNAH14-derived circRNA related to the splice acceptor variant chr1:224952669:G>A and is highly expressed in plasma exosomes in both healthy controls and cancer patients; the study does not report a clear disease-specific up/down change or functional mechanism for this circRNA.
Confidence score:

0.1768
Other information
Title:

Machine Learning-Based Comparative Analysis of Pan-Cancer and Pan-Normal Tissues Identifies Pan-Cancer Tissue-Enriched circRNAs Related to Cancer Mutations as Potential Exosomal Biomarkers.

Journal: Frontiers in oncology
Published: 2021
PubMed ID: 34604037
Study type:

bioinformatics study
Data availability: exoRbase (Sequence Read Archive raw RNA sequencing data); Supplementary Material
Code availability: GitHub repository ()