circRNA basic information
circBase ID: -
Name: hsa_circ_DLG1
Synonym: hsa_circ_chr3_196802707_196817897_R
Host Gene: DLG1
Genomic location(hg19): chr3:196802707-196817897:.
Genomic location(hg38): chr3:197075836-197091026:.
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0004975
MONDO name: Alzheimer disease
Disease details: Alzheimer’s Disease
Disease DO ID:
 10652
Disease MeSH ID:
 D000544
Disease NCIt ID:
 C2866
Disease ICD11 ID:
 1611724421
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

frontal lobe; temporal cortex; hippocampus; plasma
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UN
Associated gene: -
Associated microRNA: -
Biological function: directly associated to neuronal strength and memory loss
Molecular mechanism: -
Biological pathway or process:

other pathway/process (other)
Detected method:
S
Validation methods:

RNA-seq; Bioinformatics Analysis
Clinical significance:

good candidates for biomarkers
Description:

The DLG1-derived circRNA hsa_circ_chr3_196802707_196817897_R is reported as AD-associated and discussed as being linked to neuronal strength and memory loss; no experimental mechanistic validation was performed beyond RNA-seq/bioinformatic analyses.
Confidence score:

0.1768
Other information
Title:

Systematic Identification of circRNAs in Alzheimer's Disease.

Journal: Genes
Published: 2021
PubMed ID: 34440432
Study type:

bioinformatics study
Data availability: GSE53697; GSE110731; GSE67333; GSE104704; GSE161199; PRJNA574438
Code availability: -