| Expression pattern: |
UP |
| Associated gene: |
SERPINE1, COL1A1, MET, DKK1 |
| Associated microRNA: |
hsa_miR_145-5p, hsa_miR_133a-3p, hsa_miR_1-3p, hsa_miR_133b |
| Biological function: |
might contribute to GC progression and prognosis |
| Molecular mechanism: |
Predicted ceRNA regulation via multiple circRNA-miRNA-mRNA axes |
| Biological pathway or process: |
ceRNA regulation (other) |
| Detected method: |
M
|
| Validation methods: |
Microarray; Bioinformatics Analysis |
| Clinical significance: |
might contribute to GC progression and prognosis |
| Description: |
hsa_circ_0058097 is computationally identified as up-regulated in gastric cancer tissues and predicted as a hub circRNA in a ceRNA network. It may sponge multiple miRNAs (including hsa_miR_145-5p, hsa_miR_133a-3p, hsa_miR_133b and hsa_miR_1-3p) to regulate targets such as SERPINE1, COL1A1 and DKK1, potentially contributing to GC progression and prognosis. |
| Confidence score: |
0.1768 |