circRNA basic information
circBase ID: -
Name: hsa_circ_RIC3
Synonym: -
Host Gene: hsa-miR-204-5p
 
 
 
Disease basic information
DO ID:
 62
DO name: aortic valve disease
Disease details: aortic valve calcification
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: DPP4
Associated microRNA: hsa-miR-204-5p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

melatonin ameliorates aortic valve calcification via the regulation of CircRIC3/miR-204-5p/DPP4 signaling in hVICs; therefore, melatonin medication might be considered a novel pharmaceutical strategy for CAVD treatment.
Other information
Title:

Melatonin ameliorates aortic valve calcification via the regulation of circular RNA CircRIC3/miR-204-5p/DPP4 signaling in valvular interstitial cells.

Journal: J Pineal Res
Published: 2020/5/6
PubMed ID: 32369647