circRNA basic information
circBase ID: hsa_circ_0000267
Name: -
Synonym: -
Host Gene: -
Genomic location(hg19): chr10:126370175-126370948:-
Genomic location(hg38): chr10:124681606-124682379:-
Subcellular localization: extracellular vesicle
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0007254
MONDO name: breast cancer
Disease details: breast cancer
Disease DO ID:
 1612
Disease MeSH ID:
 -
Disease NCIt ID:
 C9335
Disease ICD11 ID:
 1047754165
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

plasma
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: -
Molecular mechanism: -
Biological pathway or process:

not specified
Detected method:
Q
S
Validation methods:

RNA-seq; RT-qPCR; Clinical Sample Validation; ROC Analysis; Bioinformatics Analysis
Clinical significance:

Biomarker for breast cancer diagnosis (part of nine-circRNA classifier BCExoC).
Description:

hsa_circ_0000267 is up-regulated in plasma EVs in breast cancer and is included in the BCExoC diagnostic signature.
Confidence score:

0.5047
Other information
Title:

Plasma-Derived Extracellular Vesicles Circular RNAs Serve as Biomarkers for Breast Cancer Diagnosis.

Journal: Frontiers in oncology
Published: 2021
PubMed ID: 34900700
Study type:

combined biological and clinical study
Data availability: -
Code availability: -