circRNA basic information
circBase ID: -
Name: -
Synonym: HPV18 circE7
Host Gene: -
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0002974
MONDO name: cervical cancer
Disease details: cervical cancer
Disease DO ID:
 4362
Disease MeSH ID:
 -
Disease NCIt ID:
 C9311
Disease ICD11 ID:
 1256072522
Disease OMIM ID:
 603956
Species: Virus
Species details: Human papillomavirus 18
Tissue specimen:

-
Cell lines:

SW-756
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UN
Associated gene: -
Associated microRNA: -
Biological function: -
Molecular mechanism: -
Biological pathway or process:

not specified
Detected method:
S
Validation methods:

RNA-seq; Bioinformatics Analysis
Clinical significance:

present in TCGA RNA-Seq datasets (HPV18+ patient tumors show frequent backsplices consistent with HPV18 circE7)
Description:

HPV18 circE7 was identified computationally from RNA-seq (including SW-756 cells and TCGA HPV-positive tumors), but it was not robustly detectable by RT-PCR or northern blot in tested HPV18+ cell lines; no functional/mechanistic assays were reported for HPV18 circE7.
Confidence score:

0.1768
Other information
Title:

Transforming activity of an oncoprotein-encoding circular RNA from human papillomavirus.

Journal: Nature communications
Published: 2019
PubMed ID: 31127091
Study type:

combined biological and clinical study
Data availability: TCGA CESC; TCGA HNSC
Code availability: https://github.com/jiwoongbio/vircircRNA