circRNA basic information
circBase ID: hsa_circ_0004913
Name: hsa_circ_TEX2
Synonym: circTEX2
Host Gene: TEX2
Genomic location(hg19): chr17:62248459-62265775:-
Genomic location(hg38): chr17:64171099-64188415:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0007256
MONDO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Disease DO ID:
 684, 686
Disease MeSH ID:
 D006528
Disease NCIt ID:
 C3099
Disease ICD11 ID:
 1294035808
Disease OMIM ID:
 114550
Species: Human
Species details: Homo sapiens
Tissue specimen:

liver cancer tissues; normal tissues; tumor tissues
Cell lines:

SMMC-7721
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: unknown
Molecular mechanism: not specified
Biological pathway or process:

not specified
Detected method:
Q
M
Validation methods:

Microarray; RT-qPCR; Clinical Sample Validation; Bioinformatics Analysis
Clinical significance:

potentially valuable diagnostic biomarkers for HCC treatment
Description:

hsa_circ_0004913 (circTEX2) was identified from GEO circRNA microarrays as differentially expressed in HCC and its up-regulation was validated by RT-qPCR in SMMC-7721 cells. The study suggests it may serve as a potential diagnostic biomarker for HCC, but no specific miRNA/mRNA axis was defined for this circRNA in the final regulatory conclusions.
Confidence score:

0.4032
Other information
Title:

Identification and integrated analysis of hepatocellular carcinoma-related circular RNA signature.

Journal: Annals of translational medicine
Published: 2020
PubMed ID: 32355738
Study type:

combined biological and clinical study
Data availability: GSE94508; GSE97332; TCGA-LIHC; GTEx
Code availability: -