circRNA basic information
circBase ID: hsa_circ_0103232
Name: hsa_circ_OCA2
Synonym: circ_0103232
Host Gene: hsa-miR-661
 
 
 
Disease basic information
DO ID:
 1909
DO name: melanoma
Disease details: melanoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: melanoma cell lines (SKMel1, A375, A875), normal human epidermal melanocytes (NHEM)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-661
Biological function: Silencing hsa_circ_0103232 suppressed melanoma cell viability, proliferation, migration, invasion, and epithelial-mesenchymal transition (EMT)
Molecular mechanism: Hsa_circ_0103232 functioned as a sponge of hsa-miR-661 to increase RAB3D expression.
Survival: -
Supported No.:
 1
Description:

Hsa_circ_0103232 is a tumor promoter in melanoma to enhance malignant phenotype and growth in vivo via sponging miR-661/RAB3D. Hsa_circ_0103232 may be a novel target for melanoma treatment.
Other information
Title:

Hsa_circ_0103232 promotes melanoma cells proliferation and invasion via targeting miR-661/RAB3D.

Journal: Cell Cycle
Published: 2022/5/14
PubMed ID: 35549813