circRNA basic information
circBase ID: -
Name: hsa_circ_ADAMTS17
Synonym: hsa_circRNA_000596
Host Gene: ADAMTS17
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0002974
MONDO name: cervical cancer
Disease details: cervical cancer
Disease DO ID:
 4362
Disease MeSH ID:
 -
Disease NCIt ID:
 C9311
Disease ICD11 ID:
 1256072522
Disease OMIM ID:
 603956
Species: Human
Species details: Homo sapiens
Tissue specimen:

-
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: CHEK1, CEP55, KIF23, RACGAP1
Associated microRNA: hsa-miR-15b
Biological function: May function as a competing endogenous RNA (ceRNA) and serve critical roles in cervical cancer.
Molecular mechanism: ceRNA mechanism (circRNA-miRNA-mRNA network).
Biological pathway or process:

ceRNA regulation (other)
Detected method:
M
Validation methods:

Microarray; Bioinformatics Analysis
Clinical significance:

-
Description:

hsa_circRNA_000596 is upregulated in cervical cancer and is predicted to act as a ceRNA by sponging hsa-miR-15b to regulate hub genes including CHEK1, CEP55, KIF23 and RACGAP1 within a constructed circRNA-miRNA-mRNA network.
Confidence score:

0.1768
Other information
Title:

Reconstruction and analysis of circRNA‑miRNA‑mRNA network in the pathology of cervical cancer.

Journal: Oncology reports
Published: 2019
PubMed ID: 30816541
Study type:

bioinformatics study
Data availability: GSE102686; GSE30656; GSE63514; TCGA-CESC
Code availability: -