circRNA basic information
circBase ID: hsa_circ_0003028
Name: hsa_circ_FUT8
Synonym: hsa_circ_00003028
Host Gene: FUT8
Genomic location(hg19): chr14:66028054-66028484:+
Genomic location(hg38): chr14:65561336-65561766:+
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0005575
MONDO name: colorectal cancer
Disease details: colorectal cancer
Disease DO ID:
 5672, 9256
Disease MeSH ID:
 -
Disease NCIt ID:
 C4978
Disease ICD11 ID:
 -
Disease OMIM ID:
 114500
Species: Human
Species details: Homo sapiens
Tissue specimen:

plasma
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: circulating diagnostic biomarker candidate in CRC; associated with primary tumor location (left vs right colon)
Molecular mechanism: not specified
Biological pathway or process:

not specified
Detected method:
Q
Validation methods:

RT-qPCR; RNase R Treatment; Clinical Sample Validation; ROC Analysis; Cohort Study
Clinical significance:

plasma level increased in CRC; ROC supports diagnostic value
Description:

hsa_circ_0003028 is up-regulated in plasma from CRC patients and shows statistically significant diagnostic accuracy by ROC analysis. Its plasma level is higher in patients with left-sided primary colon tumors compared with right-sided tumors.
Confidence score:

0.5727
Other information
Title:

New Circulating Circular RNAs with Diagnostic and Prognostic Potential in Advanced Colorectal Cancer.

Journal: International journal of molecular sciences
Published: 2021
PubMed ID: 34948079
Study type:

clinical study
Data availability: available on request from the corresponding author at e-mail: maria.radanova@mu-varna.bg
Code availability: -