circRNA basic information
circBase ID: -
Name: -
Synonym: hsa_circ_000185
Host Gene: -
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0000831
MONDO name: thrombotic disease
Disease details: deep vein thrombosis
Disease DO ID:
 0060903
Disease MeSH ID:
 D013927
Disease NCIt ID:
 C26891
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

blood
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DN
Associated gene: -
Associated microRNA: hsa-miR-1273h-5p, hsa-miR-5787, hsa-miR-619-5p, hsa-miR-7851-3p, hsa-miR-1273g-3p
Biological function: Significantly down-regulated in DVT blood samples; specific biological function was not experimentally tested.
Molecular mechanism: Predicted circRNA-miRNA interaction through MREs; no experimentally validated downstream mechanism.
Biological pathway or process:

ceRNA regulation (other)
Detected method:
Q
M
Validation methods:

RNase R Treatment; Microarray; RT-qPCR; Clinical Sample Validation; Bioinformatics Analysis
Clinical significance:

Differential expression in DVT blood samples was validated by qRT-PCR.
Description:

hsa_circ_000185 was significantly down-regulated in DVT patient blood samples and validated by qRT-PCR. Its predicted miRNA interactions were reported, but its functional role in DVT was not experimentally characterized.
Confidence score:

0.5135
Other information
Title:

Microarray profile of circular RNAs identifies hsa_circ_000455 as a new circular RNA biomarker for deep vein thrombosis.

Journal: Vascular
Published: 2022
PubMed ID: 34024202
Study type:

combined biological, clinical and bioinformatics study
Data availability: Data available on request; Supplemental material for this article is available online
Code availability: -