circRNA basic information
circBase ID: hsa_circ_0004524
Name: hsa_circ_CEP70
Synonym: -
Host Gene: CEP70
Genomic location(hg19): chr3:138289159-138291774:-
Genomic location(hg38): chr3:138570317-138572932:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0008903
MONDO name: lung cancer
Disease details: lung cancer
Disease DO ID:
 1324
Disease MeSH ID:
 -
Disease NCIt ID:
 C7377
Disease ICD11 ID:
 -
Disease OMIM ID:
 211980
Species: Human
Species details: Homo sapiens
Tissue specimen:

-
Cell lines:

A549; NCI-H1299
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DN
Associated gene: -
Associated microRNA: -
Biological function: unknown
Molecular mechanism: Predicted circRNA-miRNA interactions (bioinformatics) for validated circRNAs; not specified for this circRNA.
Biological pathway or process:

not specified
Detected method:
Q
S
Validation methods:

RNA-seq; RT-qPCR; Bioinformatics Analysis
Clinical significance:

-
Description:

hsa_circ_0004524 is significantly down-regulated in irradiated NSCLC cells and was validated by RT-qPCR. No circRNA-specific functional assays or downstream pathway were reported for this circRNA.
Confidence score:

0.2465
Other information
Title:

RNAseq profiling of circRNA expression in radiation-treated A549 cells and bioinformatics analysis of radiation-related circRNA-miRNA networks.

Journal: Oncology letters
Published: 2020
PubMed ID: 32724397
Study type:

biological research
Data availability: GSE124396
Code availability: -