circRNA basic information
circBase ID: hsa_circ_0008602
Name: hsa_circ_GUCY1A2
Synonym: CircGUCY1A2
Host Gene: GUCY1A2
Genomic location(hg19): chr11:106849344-106856857:-
Genomic location(hg38): chr11:106978618-106986131:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0008315
MONDO name: prostate cancer
Disease details: prostate cancer
Disease DO ID:
 10283
Disease MeSH ID:
 D011471
Disease NCIt ID:
 C7378
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

-
Cell lines:

RWPE-1; 22RV1; PC3
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DS
Associated gene: -
Associated microRNA: miR200c, miR-200b
Biological function: may affect tumor formation
Molecular mechanism: predicted miRNA sponge interaction with miR200c and miR-200b
Biological pathway or process:

proliferation (other); ceRNA regulation (other)
Detected method:
Q
S
Validation methods:

circRNA-seq; RNase R Treatment; RT-qPCR; Bioinformatics Analysis
Clinical significance:

-
Description:

CircGUCY1A2 (hsa_circ_0008602) shows differential expression across prostate cancer cell line comparisons and is predicted to bind miR200c/miR-200b, implying a potential ceRNA interaction related to PCa development.
Confidence score:

0.4276
Other information
Title:

Profiling and bioinformatics analyses of differential circular RNA expression in prostate cancer cells.

Journal: Future science OA
Published: 2018
PubMed ID: 30416748
Study type:

biological research
Data availability: -
Code availability: -