circRNA basic information
circBase ID: hsa_circ_0004015
Name: -
Synonym: -
Host Gene: -
Genomic location(hg19): chr7:90355880-90377090:+
Genomic location(hg38): chr7:90726566-90747775:+
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0002974
MONDO name: cervical cancer
Disease details: cervical cancer
Disease DO ID:
 4362
Disease MeSH ID:
 -
Disease NCIt ID:
 C9311
Disease ICD11 ID:
 1256072522
Disease OMIM ID:
 603956
Species: Human
Species details: Homo sapiens
Tissue specimen:

-
Cell lines:

HeLa
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: ZYX, PRKAR1A, BTAF1, LRP3, ETS1
Associated microRNA: hsa-miR-3163, hsa-miR-3065-5p, hsa-miR-551b-5p, hsa-miR-4311, hsa-miR-875-3p
Biological function: -
Molecular mechanism: ceRNA/miRNA sponge (predicted network)
Biological pathway or process:

ceRNA regulation (other)
Detected method:
Q
S
Validation methods:

RNA-seq; RT-qPCR; Bioinformatics Analysis
Clinical significance:

-
Description:

hsa_circ_0004015 is up-regulated in irradiated HeLa cells and is highlighted in a predicted circRNA-miRNA-mRNA network, where it may sponge several miRNAs (e.g., hsa-miR-3163) to regulate multiple target genes relevant to radioresistance.
Confidence score:

0.2465
Other information
Title:

Comprehensive circular RNA expression profile in radiation-treated HeLa cells and analysis of radioresistance-related circRNAs.

Journal: PeerJ
Published: 2018
PubMed ID: 29922514
Study type:

biological research
Data availability: Duo, Yu (2018): Raw Data. figshare. Fileset.
Code availability: -