circRNA basic information
circBase ID: -
Name: hsa_circ_CREBBP
Synonym: circCREBBP (Chr 16: 3,850,297-3,851,009)
Host Gene: CREBBP
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0007254
MONDO name: breast cancer
Disease details: primary breast cancer
Disease DO ID:
 1612
Disease MeSH ID:
 -
Disease NCIt ID:
 C9335
Disease ICD11 ID:
 1047754165
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

primary breast tumors
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UN
Associated gene: -
Associated microRNA: -
Biological function: Potential functional relevance evaluated in breast cancer cell lines (no specific functional outcome reported for circCREBBP in provided text).
Molecular mechanism: not specified
Biological pathway or process:

not specified
Detected method:
Q
S
Validation methods:

RNA-seq; Back-Splice Junction PCR / divergent primers PCR; RT-qPCR; Clinical Sample Validation
Clinical significance:

-
Description:

circCREBBP (genomic region chr16:3850297-3851009) was detected by RNA-seq and confirmed in an independent pool of primary breast tumors using PCR-based assays and RT-qPCR. The study notes it as a candidate with poor correlation to linear CREBBP, suggesting possible specific regulation, but provides no specific downstream mechanism or clinical association for circCREBBP in the provided text.
Confidence score:

0.4773
Other information
Title:

The circular RNome of primary breast cancer.

Journal: Genome research
Published: 2019
PubMed ID: 30692147
Study type:

biological research
Data availability: EGAS00001001178
Code availability: -