circRNA basic information
circBase ID: -
Name: hsa_circ_ABCC1
Synonym: circRNA_101717 / hsa_circRNA_101717
Host Gene: ABCC1
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0009831
MONDO name: malignant pancreatic neoplasm
Disease details: pancreatic cancer
Disease DO ID:
 1793
Disease MeSH ID:
 -
Disease NCIt ID:
 C9005
Disease ICD11 ID:
 542147910
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

pancreatic cancer tissues; paracancerous tissues
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: miR-506-3p, let-7e-5p, miR-124-3p, miR-877-5p, let-7c-5p
Biological function: may act as a miRNA sponge related to miR-506
Molecular mechanism: miRNA sponge (ceRNA-like) with miR-506
Biological pathway or process:

ceRNA regulation (other)
Detected method:
Q
M
Validation methods:

Microarray; RT-qPCR; RNase R Treatment; Clinical Sample Validation; Bioinformatics Analysis
Clinical significance:

-
Description:

circRNA_101717 (hsa_circRNA_101717; host gene ABCC1) is up-regulated in pancreatic cancer and was predicted to bind miR-506; its higher level was negatively correlated with miR-506 in tumor tissues, supporting a miRNA-sponge role.
Confidence score:

0.5135
Other information
Title:

Microarray expression profile analysis of circular RNAs in pancreatic cancer.

Journal: Molecular medicine reports
Published: 2018
PubMed ID: 29620241
Study type:

combined biological and clinical study
Data availability: GSE79634
Code availability: -