breast cancer tumor tissues; corresponding nontumorous tissues
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not specified
circRNA-seq; RT-qPCR; RNase R Treatment; divergent primers PCR; Clinical Sample Validation
hsa_circ_0102273 was identified by circRNA sequencing as up-regulated in breast cancer tumor tissues and its increase was validated by RT-qPCR in clinical tissue pairs; no downstream mechanism or functional assays were reported for this circRNA.
0.5531
Silencing of hsa_circ_0004771 inhibits proliferation and induces apoptosis in breast cancer through activation of miR-653 by targeting ZEB2 signaling pathway.
combined biological and clinical study