| Expression pattern: |
DN |
| Associated gene: |
- |
| Associated microRNA: |
- |
| Biological function: |
potential roles in carcinogenesis as ceRNA for regulation of miRNA-mRNA network |
| Molecular mechanism: |
ceRNA mechanism (circRNA-miRNA-mRNA network) (bioinformatics-predicted) |
| Biological pathway or process: |
ceRNA regulation (other); other pathway/process (other) |
| Detected method: |
S
|
| Validation methods: |
circRNA-seq; RNA-seq; Bioinformatics Analysis; Clinical Sample Validation |
| Clinical significance: |
candidate diagnostic biomarkers or potential therapeutic targets (as a group of circRNAs) |
| Description: |
circPIEZO1-3 is one of the top down-regulated circRNAs in colorectal cancer tissues. The study includes it as a hub circRNA in a bioinformatically constructed ceRNA (circRNA-miRNA-mRNA) network potentially involved in CRC carcinogenesis. |
| Confidence score: |
0.4685 |