circRNA basic information
circBase ID: -
Name: hsa_circ_AKR1E2
Synonym: -
Host Gene: AKR1E2
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0006046
MONDO name: ovarian serous cystadenocarcinoma
Disease details: ovarian serous cystadenocarcinoma
Disease DO ID:
 5746
Disease MeSH ID:
 -
Disease NCIt ID:
 C7978
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

tumor tissues; para-tumor tissues
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: miR-608, let-7
Biological function: potential biomarker
Molecular mechanism: predicted miRNA sponge activity (targets miR-608 and let-7 family miRNAs)
Biological pathway or process:

ceRNA regulation (other)
Detected method:
S
Validation methods:

RNA-seq; Bioinformatics Analysis
Clinical significance:

could be used as potential biomarkers in response to ovarian serous cystadenocarcinoma
Description:

hsa_circ_AKR1E2 was identified as enriched in tumor tissues and predicted to target ovarian cancer-related miRNAs including miR-608 and multiple let-7 family members, supporting a putative ceRNA/miRNA-sponge role and biomarker candidacy.
Confidence score:

0.1768
Other information
Title:

The circular RNA expression profile in ovarian serous cystadenocarcinoma reveals a complex circRNA-miRNA regulatory network.

Journal: BMC medical genomics
Published: 2021
PubMed ID: 34857007
Study type:

combined biological and clinical study
Data availability: PRJCA002938
Code availability: -