| Expression pattern: |
DN |
| Associated gene: |
AR |
| Associated microRNA: |
- |
| Biological function: |
May regulate HNF3A pathway via AR (inferred from correlation/ceRNA analysis). |
| Molecular mechanism: |
Predicted ceRNA mechanism in a constructed ceRNA network, with AR as target gene; upstream regulator of AR signaling suggested by network context. |
| Biological pathway or process: |
other pathway/process (other); ceRNA regulation (other) |
| Detected method: |
S
|
| Validation methods: |
RNA-seq; Bioinformatics Analysis |
| Clinical significance: |
Might be associated with prognosis of HCC patients (inferred indirectly via target gene AR/GOT2 survival associations). |
| Description: |
hsa_circ_0008774 is a downregulated circRNA in an HCC ceRNA network and is computationally linked to AR as a target gene. The study suggests it may act upstream of AR signaling and relate to HNF3A-pathway-associated gene programs, but lacks experimental validation for this circRNA. |
| Confidence score: |
0.1768 |