circRNA basic information
circBase ID: hsa_circ_0001544
Name: hsa_circ_NR3C1
Synonym: hsa_circRNA_001544
Host Gene: NR3C1
Genomic location(hg19): chr5:142779864-142780072:-
Genomic location(hg38): chr5:143400299-143400507:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0005306
MONDO name: ankylosing spondylitis
Disease details: ankylosing spondylitis
Disease DO ID:
 7147
Disease MeSH ID:
 D013167
Disease NCIt ID:
 C84564
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

peripheral blood mononuclear cells (PBMCs); peripheral blood
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: has-miR-3681-5p, hsa-miR-3691-5p, hsa-miR-450b-5p, hsa-miR-412-5p, hsa-miR-6855 -5p
Biological function: Potential molecular marker for AS diagnosis.
Molecular mechanism: not specified
Biological pathway or process:

not specified
Detected method:
Q
M
Validation methods:

Microarray; RT-qPCR; Clinical Sample Validation; ROC Analysis; Bioinformatics Analysis
Clinical significance:

ROC curve analysis showed that hsa_circRNA_001544 was statistically significant for distinguishing AS from HC (AUC ~0.720).
Description:

hsa_circRNA_001544 (hsa_circ_0001544; host gene NR3C1) is up-regulated in PBMCs from AS patients and shows diagnostic potential based on ROC analysis.
Confidence score:

0.5047
Other information
Title:

Circular RNAs in peripheral blood mononuclear cells from ankylosing spondylitis.

Journal: Chinese medical journal
Published: 2021
PubMed ID: 34670246
Study type:

combined biological and clinical study
Data availability: -
Code availability: -