circRNA basic information
circBase ID: hsa_circ_0005273
Name: hsa_circ_PTK2
Synonym: circPTK2
Host Gene: PTK2
Genomic location(hg19): chr8:141710989-141716304:-
Genomic location(hg38): chr8:140700890-140706205:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0004986
MONDO name: urinary bladder carcinoma
Disease details: bladder carcinoma
Disease DO ID:
 4007
Disease MeSH ID:
 -
Disease NCIt ID:
 C4912
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

bladder carcinoma tissue; para-carcinoma tissue
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: unknown
Molecular mechanism: -
Biological pathway or process:

not specified
Detected method:
Q
M
Validation methods:

Microarray; RNase R Treatment; RT-qPCR; divergent primers PCR; Clinical Sample Validation
Clinical significance:

potentially valuable diagnostic biomarker
Description:

circPTK2 (hsa_circ_0005273) is significantly up-regulated in bladder carcinoma tissues and was validated by qRT-PCR in clinical paired samples, suggesting potential diagnostic relevance.
Confidence score:

0.5541
Other information
Title:

Screening differential circular RNA expression profiles reveals the regulatory role of circTCF25-miR-103a-3p/miR-107-CDK6 pathway in bladder carcinoma.

Journal: Scientific reports
Published: 2016
PubMed ID: 27484176
Study type:

combined biological and clinical study
Data availability: -
Code availability: -