circRNA basic information
circBase ID: hsa_circ_0007444
Name: hsa_circ_RHOBTB3
Synonym: circRHOBTB3
Host Gene: hsa-miR-600
 
 
 
Disease basic information
DO ID:
 3498
DO name: pancreatic ductal adenocarcinoma
Disease details: pancreatic ductal adenocarcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
UP
Associated gene: NACC1
Associated microRNA: hsa-miR-600
Biological function: -
Molecular mechanism: -
Survival: poor
Supported No.:
 1
Description:

FUS-mediated circRHOBTB3 functions as a tumor activator to promote PDAC cell proliferation by modulating miR-600/NACC1/Akt/mTOR axis regulated autophagy.
Other information
Title:

FUS-induced circRHOBTB3 facilitates cell proliferation via miR-600/NACC1 mediated autophagy response in pancreatic ductal adenocarcinoma.

Journal: J Exp Clin Cancer Res
Published: 2021/8/22
PubMed ID: 34416910