circRNA basic information
circBase ID: hsa_circ_0003162
Name: hsa_circ_BBS9
Synonym: -
Host Gene: BBS9
Genomic location(hg19): chr7:33185853-33217203:+
Genomic location(hg38): chr7:33146241-33177591:+
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
0005061
MONDO name: lung adenocarcinoma
Disease details: lung adenocarcinoma
Disease DO ID:
3910
Disease MeSH ID:
C538231
Disease NCIt ID:
C3512
Disease ICD11 ID:
-
Disease OMIM ID:
-
Species: Human
Species details: Homo sapiens
Tissue specimen:

LUAD tissues; normal lung tissues

Cell lines:

-

In vivo animal model:

-

circRNA-disease information
Expression pattern:
DN
Associated gene: -
Associated microRNA: -
Biological function: Potential miRNA sponge (ceRNA) in LUAD
Molecular mechanism: ceRNA mechanism via miRNA response elements (MREs) within a circRNA-miRNA-mRNA network
Biological pathway or process:

ceRNA regulation (other); PI3K/AKT (other); HIF-1 signaling (other); other pathway/process (other)

Detected method:
M
Validation methods:

Microarray; Bioinformatics Analysis

Clinical significance:

Could have diagnostic value for LUAD

Description:

hsa_circ_0003162 is down-regulated in LUAD and was identified bioinformatically as a cancer-specific circRNA candidate with predicted MREs, supporting a potential ceRNA/miRNA-sponge role and diagnostic relevance.

Confidence score:

0.1768

Other information
Title:

Identification of Differentially Expressed Circular RNAs as miRNA Sponges in Lung Adenocarcinoma.

Journal: Journal of oncology
Published: 2021
PubMed ID: 34539783
Study type:

bioinformatics study

Data availability: GSE101586; GSE101684
Code availability: -