circRNA basic information
circBase ID: hsa_circ_0001955
Name: hsa_circ_CSNK1G1
Synonym: -
Host Gene: CSNK1G1
Genomic location(hg19): chr15:64495280-64508912:-
Genomic location(hg38): chr15:64203081-64216713:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0005131
MONDO name: cervical carcinoma
Disease details: cervical carcinogenesis
Disease DO ID:
 2893
Disease MeSH ID:
 -
Disease NCIt ID:
 C9039
Disease ICD11 ID:
 1743710977
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

cervical specimens
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: CDK1, NEDD4L
Associated microRNA: hsa-miR-6719-3p, hsa-miR-1277-5p
Biological function: Potential role in cervical carcinogenesis (no direct functional assay reported for this circRNA).
Molecular mechanism: ceRNA mechanism via hsa-miR-6719-3p/CDK1 and hsa-miR-1277-5p/NEDD4L.
Biological pathway or process:

ceRNA regulation (other)
Detected method:
Q
M
Validation methods:

Microarray; RT-qPCR; Clinical Sample Validation; Bioinformatics Analysis
Clinical significance:

-
Description:

hsa_circ_0001955 is continuously upregulated from NC to HSIL and CSCC. The study supports a ceRNA role for hsa_circ_0001955 involving hsa-miR-6719-3p/CDK1 and hsa-miR-1277-5p/NEDD4L during cervical carcinogenesis.
Confidence score:

0.4032
Other information
Title:

Comprehensive Analysis of circRNA Expression Profiles During Cervical Carcinogenesis.

Journal: Frontiers in oncology
Published: 2021
PubMed ID: 34532284
Study type:

combined biological and clinical study
Data availability: GSE166466
Code availability: -