circRNA basic information
circBase ID: hsa_circ_0004370
Name: -
Synonym: -
Host Gene: -
Genomic location(hg19): chr1:170688866-170695542:+
Genomic location(hg38): chr1:170719725-170726401:+
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0001056
MONDO name: gastric cancer
Disease details: gastric cancer
Disease DO ID:
 10534
Disease MeSH ID:
 -
Disease NCIt ID:
 C9331
Disease ICD11 ID:
 1397617262
Disease OMIM ID:
 613659
Species: Human
Species details: Homo sapiens
Tissue specimen:

tumor tissue; adjacent normal mucosal tissues
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DS
Associated gene: THBS1, CALM1
Associated microRNA: hsa-miR-648
Biological function: May play central roles in regulating the development of GC (inferred from ceRNA axis construction).
Molecular mechanism: ceRNA mechanism (circRNA-miRNA-mRNA network).
Biological pathway or process:

ceRNA regulation (other)
Detected method:
M
Validation methods:

Microarray; Bioinformatics Analysis
Clinical significance:

-
Description:

This paper’s ceRNA network analysis associates hsa_circ_0004370 with hsa-miR-648 and downstream THBS1/CALM1 in gastric cancer. The finding is bioinformatics-based with no direct experimental confirmation reported.
Confidence score:

0.1768
Other information
Title:

Comprehensive Analysis of a circRNA-miRNA-mRNA Network to Reveal Potential Inflammation-Related Targets for Gastric Adenocarcinoma.

Journal: Mediators of inflammation
Published: 2020
PubMed ID: 32801999
Study type:

bioinformatics study
Data availability: GSE83521; GSE78091; GSE33651
Code availability: -