circRNA basic information
circBase ID: hsa_circ_0002727
Name: -
Synonym: -
Host Gene: -
Genomic location(hg19): chr10:88230748-88233730:-
Genomic location(hg38): chr10:86470991-86473973:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0005061
MONDO name: lung adenocarcinoma
Disease details: lung adenocarcinoma
Disease DO ID:
 3910
Disease MeSH ID:
 C538231
Disease NCIt ID:
 C3512
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

tumor tissue; adjacent normal lung tissue
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DS
Associated gene: CEP55, KIF14, PRR11
Associated microRNA: has-miR-144-3p
Biological function: -
Molecular mechanism: circRNA-associated ceRNA network; potentially regulates CEP55, KIF14 and PRR11 via has-miR-144-3p
Biological pathway or process:

ceRNA regulation (other); prognosis (other)
Detected method:
M
Validation methods:

Microarray; Bioinformatics Analysis
Clinical significance:

-
Description:

This circRNA was identified as a differentially expressed circRNA in LUAD and included in a constructed circRNA-miRNA-mRNA ceRNA network. It was proposed to interact with has-miR-144-3p and thereby potentially regulate CEP55, KIF14, and PRR11, influencing LUAD progression and prognosis.
Confidence score:

0.1768
Other information
Title:

Prognostic Nomogram Based on Circular RNA-Associated Competing Endogenous RNA Network for Patients with Lung Adenocarcinoma.

Journal: Oxidative medicine and cellular longevity
Published: 2021
PubMed ID: 34497684
Study type:

bioinformatics study
Data availability: GSE101586; GSE101684; GSE42127; TCGA-LUAD
Code availability: -