circRNA basic information
circBase ID: -
Name: hsa_circ_PIK3C3
Synonym: circPIK3C3
Host Gene: PIK3C3
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: exosome
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0005411
MONDO name: gallbladder cancer
Disease details: gallbladder cancer
Disease DO ID:
 3121
Disease MeSH ID:
 -
Disease NCIt ID:
 C7481
Disease ICD11 ID:
 922082116
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

plasma-derived exosomes
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DS
Associated gene: -
Associated microRNA: -
Biological function: -
Molecular mechanism: -
Biological pathway or process:

ceRNA regulation (other)
Detected method:
S
Validation methods:

RNA-seq; Bioinformatics Analysis
Clinical significance:

-
Description:

circPIK3C3 is significantly differentially expressed in plasma-derived exosomes from gallbladder cancer patients compared with xantho-granulomatous cholecystitis controls. It was highlighted as a widely expressed DE exosomal circRNA in the RNA-seq dataset, with only computational ceRNA/miRNA-target analyses reported and no direct experimental functional validation.
Confidence score:

0.1768
Other information
Title:

Exploration of differentially-expressed exosomal mRNAs, lncRNAs and circRNAs from serum samples of gallbladder cancer and xantho-granulomatous cholecystitis patients.

Journal: Bioengineered
Published: 2021
PubMed ID: 34486489
Study type:

combined biological and clinical study
Data availability: GSE166915
Code availability: -