circRNA basic information
circBase ID: -
Name: hsa_circ_HIPK3
Synonym: circ-homeodomain-interacting protein kinase 3 / circHIPK3
Host Gene: HIPK3
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0021042
MONDO name: glioma
Disease details: glioma
Disease DO ID:
 -
Disease MeSH ID:
 D005910
Disease NCIt ID:
 C3059
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

-
Cell lines:

U87; U87MG
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UN
Associated gene: -
Associated microRNA: -
Biological function: AGPS silencing significantly downregulated circHIPK3 expression in human glioma U87MG cells; no direct functional assay of circHIPK3 was reported.
Molecular mechanism: AGPS silencing regulates circHIPK3 expression; no direct circHIPK3 molecular mechanism was defined.
Biological pathway or process:

not specified
Detected method:
Q
Validation methods:

RT-qPCR; Transfection
Clinical significance:

-
Description:

In this glioma cell study, circHIPK3 was measured as a circular RNA whose expression was significantly reduced after AGPS silencing in U87MG cells. The paper did not directly test circHIPK3 function, subcellular localization, interacting partners, or clinical significance.
Confidence score:

0.2586
Other information
Title:

Tudor-staphylococcal nuclease regulates the expression and biological function of alkylglycerone phosphate synthase via nuclear factor-kappaB and microRNA-127 in human glioma U87MG cells.

Journal: Oncology letters
Published: 2018
PubMed ID: 29805677
Study type:

biological research
Data availability: All data generated or analyzed during this study are included in this published article.
Code availability: -