circRNA basic information
circBase ID: -
Name: hsa_circ_DOCK1
Synonym: hsa_circ_chr10_128859931_128908618_F
Host Gene: DOCK1
Genomic location(hg19): chr10:128859931-128908618:.
Genomic location(hg38): chr10:127061667-127110354:.
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
0004975
MONDO name: Alzheimer disease
Disease details: Alzheimer’s Disease
Disease DO ID:
10652
Disease MeSH ID:
D000544
Disease NCIt ID:
C2866
Disease ICD11 ID:
1611724421
Disease OMIM ID:
-
Species: Human
Species details: Homo sapiens
Tissue specimen:

frontal lobe; temporal cortex; hippocampus; plasma

Cell lines:

-

In vivo animal model:

-

circRNA-disease information
Expression pattern:
DS
Associated gene: -
Associated microRNA: -
Biological function: unknown
Molecular mechanism: -
Biological pathway or process:

not specified

Detected method:
S
Validation methods:

RNA-seq; Bioinformatics Analysis

Clinical significance:

-

Description:

This study reports a DOCK1-derived circRNA (hsa_circ_chr10_128859931_128908618_F) as differentially abundant in Alzheimer’s disease across public RNA-seq datasets, but its functional role and mechanism were not experimentally characterized.

Confidence score:

0.1768

Other information
Title:

Systematic Identification of circRNAs in Alzheimer's Disease.

Journal: Genes
Published: 2021
PubMed ID: 34440432
Study type:

bioinformatics study

Data availability: GSE53697; GSE110731; GSE67333; GSE104704; GSE161199; PRJNA574438
Code availability: -