circRNA basic information
circBase ID: hsa_circ_0001730
Name: -
Synonym: -
Host Gene: -
Genomic location(hg19): chr7:100410368-100410830:-
Genomic location(hg38): chr7:100812746-100813208:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0015459
MONDO name: nasopharyngeal carcinoma
Disease details: nasopharyngeal carcinoma
Disease DO ID:
 9261
Disease MeSH ID:
 D00007727; D000077274
Disease NCIt ID:
 C3871
Disease ICD11 ID:
 1883313543
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

nasopharyngeal carcinoma tissues; non-NPC nasopharyngeal epithelial tissues
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: Associated with NPC immune microenvironment (high expression in T cells/TIL).
Molecular mechanism: unknown
Biological pathway or process:

immune regulation (other)
Detected method:
Q
S
Validation methods:

RNA-seq; RT-qPCR; Clinical Sample Validation; Bioinformatics Analysis
Clinical significance:

-
Description:

hsa_circ_0001730 was selected from GEO differential analysis and showed high expression in NPC tissues and in T-cell populations from recurrent NPC samples by qRT-PCR; no specific downstream mechanism was reported.
Confidence score:

0.4032
Other information
Title:

Immune Microenvironment Change and Involvement of Circular RNAs in TIL Cells of Recurrent Nasopharyngeal Carcinoma.

Journal: Frontiers in cell and developmental biology
Published: 2021
PubMed ID: 34422839
Study type:

combined biological and clinical study
Data availability: GSE134797; GSE118719
Code availability: -