circRNA basic information
circBase ID: hsa_circ_0059713
Name: -
Synonym: -
Host Gene: -
Genomic location(hg19): chr20:30345209-30389603:+
Genomic location(hg38): chr20:31757406-31801800:+
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0001056
MONDO name: gastric cancer
Disease details: gastric cancer
Disease DO ID:
 10534
Disease MeSH ID:
 -
Disease NCIt ID:
 C9331
Disease ICD11 ID:
 1397617262
Disease OMIM ID:
 613659
Species: Human
Species details: Homo sapiens
Tissue specimen:

-
Cell lines:

AGS
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UN
Associated gene: MAP2, HIPK2, ANK2
Associated microRNA: hsa-miR-372-5p
Biological function: Associated with esomeprazole anti-tumor effects via a predicted ceRNA network involving MAP2, HIPK2 and ANK2 in AGS gastric cancer cells.
Molecular mechanism: ceRNA mechanism: hsa_circ_0059713 may act as a ceRNA of hsa-miR-372-5p to affect MAP2, HIPK2 and ANK2.
Biological pathway or process:

ceRNA regulation (other)
Detected method:
M
Validation methods:

Microarray; Bioinformatics Analysis
Clinical significance:

-
Description:

hsa_circ_0059713 was proposed (via bioinformatic ceRNA network analysis) to sponge hsa-miR-372-5p and thereby relate to regulation of MAP2, HIPK2 and ANK2 in AGS gastric cancer cells under esomeprazole treatment.
Confidence score:

0.1768
Other information
Title:

Esomeprazole affects the proliferation, metastasis, apoptosis and chemosensitivity of gastric cancer cells by regulating lncRNA/circRNA-miRNA-mRNA ceRNA networks.

Journal: Oncology letters
Published: 2020
PubMed ID: 33101498
Study type:

biological research
Data availability: available from the corresponding author on reasonable request
Code availability: -