circRNA basic information
circBase ID: hsa_circ_0091742
Name: -
Synonym: -
Host Gene: -
Genomic location(hg19): chrX:152770695-152775004:+
Genomic location(hg38): chrX:153505237-153509546:+
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0001056
MONDO name: gastric cancer
Disease details: gastric cancer
Disease DO ID:
 10534
Disease MeSH ID:
 -
Disease NCIt ID:
 C9331
Disease ICD11 ID:
 1397617262
Disease OMIM ID:
 613659
Species: Human
Species details: Homo sapiens
Tissue specimen:

GC tissues
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: SERPINE1, GCNT4, EPHA7
Associated microRNA: miR-145, miR-196a, miR-196b, miR-552
Biological function: might regulate target genes related to GC progression and prognosis
Molecular mechanism: Predicted ceRNA mechanism via binding miRNAs to regulate target genes
Biological pathway or process:

ceRNA regulation (other)
Detected method:
M
Validation methods:

Microarray; Bioinformatics Analysis
Clinical significance:

related to GC progression and prognosis (predicted via target genes)
Description:

hsa_circ_0091742 is computationally identified as up-regulated in gastric cancer tissues and predicted to bind miR-145, miR-196a, miR-196b and miR-552. Through these interactions it may regulate targets including SERPINE1, GCNT4 and EPHA7, potentially contributing to GC progression and prognosis.
Confidence score:

0.1768
Other information
Title:

A Robust Circular RNA-Associated Three-Gene Prognostic Signature for Patients with Gastric Cancer.

Journal: BioMed research international
Published: 2021
PubMed ID: 33969120
Study type:

bioinformatics study
Data availability: GEO; TCGA
Code availability: -