circRNA basic information
circBase ID: -
Name: hsa_circ_SHKBP1
Synonym: circ-SHKBP1
Host Gene: SHKBP1
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0021042
MONDO name: glioma
Disease details: glioma
Disease DO ID:
 -
Disease MeSH ID:
 D005910
Disease NCIt ID:
 C3059
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

blood plasma
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UN
Associated gene: DNA-oligonucleotide sequences (oDNA), DNA probes
Associated microRNA: -
Biological function: -
Molecular mechanism: -
Biological pathway or process:

not specified
Detected method:
M
Validation methods:

Clinical Sample Validation; Microarray
Clinical significance:

Potential liquid-biopsy detection marker for glioma/neoplasm of uncertain nature of the brain and central nervous system using h-k-SOI-NW chip in plasma.
Description:

This study used a high-k SOI nanowire chip to detect circ-SHKBP1 (via complementary DNA probes) in human blood plasma samples from patients with brain/CNS neoplasms of uncertain nature, demonstrating feasibility for highly sensitive liquid-biopsy-style detection. The work focuses on biosensor detection capability rather than circ-SHKBP1’s biological mechanism or expression direction in glioma.
Confidence score:

0.2995
Other information
Title:

Micro-Raman Characterization of Structural Features of High-k Stack Layer of SOI Nanowire Chip, Designed to Detect Circular RNA Associated with the Development of Glioma.

Journal: Molecules (Basel, Switzerland)
Published: 2021
PubMed ID: 34207029
Study type:

combined biological and clinical study
Data availability: -
Code availability: -